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Q Drop #4114

Started by RSS Bot, Wed Jan 25, 2023 - 07:02:25

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Q Drop #4114

https://pubmed.ncbi.nlm.nih.gov/16115318/"]Chloroquine is a potent inhibitor of SARS coronavirus infection and spread - PubMed[/url]

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30251-8/fulltext

When the protein sequence of the SARS-CoV-2 receptor binding site was analyzed, an interesting result was found. While SARS-CoV-2 is overall more similar to bat coronaviruses, the receptor binding site was more similar to SARS-CoV.

https://www.cell.com/cell/fulltext/S0092-8674(20)30262-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420302622%3Fshowall%3Dtrue"]Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein: Cell[/url]

Both SARS-CoV-2 and SARS-CoV use the same host cell receptor. It also found that, for both viruses, the viral proteins used for host cell entry bind to the receptor with the same tightness (affinity).

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Source: Q Drop #4114

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